H302-Harmful if swallowed. In thiocyanates, the organic group (or metal ion) is attached to sulfur: R−S−C≡N has a S–C single bond and a C≡N triple bond. [SCN]− is one of the pseudohalides, due to the similarity of its reactions to that of halide ions. Hazard statement(s ) H302 + H312 + H332 H412 Precautionary statement(s ) P273 P280 Harmful if swallowed, in contact with skin or if inhaled Harmful to aquatic life with long lasting effects. H332-Harmful if inhaled. If halogenated, they should be collected in container B. [14] Sodium nitroprusside, a metabolite of which is thiocyanate, is however still used for the treatment of a hypertensive emergency. MDL number MFCD00011413. Disposal: Not applicable. [SCN]− can also bridge two (M−SCN−M) or even three metals (>SCN− or −SCN<). Organic and transition metal derivatives of the thiocyanate ion can exist as "linkage isomers". Toxicity Statement: Not … 105124 View Pricing & Availability. PubChem Substance ID 24898354. SDS; CoA; Synonyms: Potassium sulfocyanide EC Number: 206-370-1 Grade: ACS,ISO,Reag. AgSCN is monoclinic with 8 molecules per unit cell. Synthesis Route Total 43 Documents >> 57-06-7. allyl isothiocyanate. MSDS: Chinese USA: Flash Point: 500°C: Symbol: GHS07: Signal Word: Warning × Organic compounds containing the functional group SCN are also called thiocyanates. Causes eye irritation … In the early 20th century, thiocyanate was used in the treatment of hypertension, but it is no longer used because of associated toxicity. - No smoking. Signal Word Warning Hazard Statements Harmful if swallowed Harmful in contact with skin Harmful if inhaled Company Fisher Scientific One Reagent Lane Fair Lawn, NJ 07410 Tel: (201) 796-7100 Acute oral toxicity Category 4 Acute dermal toxicity Category 4 Acute Inhalation Toxicity - Dusts and Mists Category 4 _____ Page 1 / 7 _____ Potassium thiocyanate Revision Date 17-Jan-2018 … 58 / Monday, March 26, 2012 / Rules and Regulations Date of issue: 04/24/2015 Version: 1.0 04/24/2015 EN (English US) Page 1 SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. Hazard class: Serious eye damage or irritation (Category 2B). Hazard Statements: Not applicable. 0. Several synthesis routes exist, the most basic being the reaction between alkyl halides and alkali thiocyanate in aqueous media. Fe(SCN)3 and [Fe(SCN)4]−. The compound has a low melting point relative to most other inorganic salts. Box 219, Batavia, IL 60510 (800) 452-1261 Chemtrec Emergency Phone Number: (800) 424-10191 Signal Word WARNING SECTION 2 — HAZARDS IDENTIFICATION Hazard class: Skin corrosion or irritation (Category 3). Potassium thiocyanate. Response: Not applicable. P270 - Do not eat, drink or smoke when using this product. Warning; Hazard Category. Use in chemical synthesis 592-88-1. In a related reaction, KSCN converts cyclohexene oxide to the corresponding episulfide.[4]. Signal Word: Not applicable. Supporting you all the way Balance Servicing; Microscope Servicing; Chemical Waste Disposal; Rapid Response Cleaning Signal Word Warning Hazard Statements H272 - May intensify fire; oxidizer Precautionary Statements P280 - Wear protective gloves/protective clothing/eye protection/face protection P221 - Take any precaution to avoid mixing with combustibles P371 + P380 + P375 - In case of major fire and large quantities: Evacuate area. 4 (H302) Acute Tox. The ‘Substance identity’ section is calculated from substance identification information from all ECHA databases. Rhodanese catalyzes the reaction of sodium nitroprusside with thiosulfate to form the metabolite thiocyanate. 4 (H312) Acute Tox. 333-20-0. potassium thiocyanate. GHS Signal word: Warning: GHS hazard statements. Storage: Not applicable. Signal word Danger. It can be painted onto a surface or kept as a colorless solution. Potassium Thiocyanate, 10% w/v Safety Data Sheet according to Federal Register / Vol. Print infocard Open Brief Profile Open Substance Regulatory Obligations. Thiocyanate (also known as rhodanide) is the anion [SCN]−. Hazard class: Skin corrosion or irritation (Category 3). Thiocyanate is analogous to the cyanate ion, [OCN]−, wherein oxygen is replaced by sulfur. Signal word (GHS US) : Warning Hazard statements (GHS US) : H272 - May intensify fire; oxidizer H315 - Causes skin irritation H319 - Causes serious eye irritation H335 - May cause respiratory irritation Precautionary statements (GHS US) : P210 - Keep away from heat, hot surfaces, open flames, sparks. [2], KSCN converts ethylene carbonate to ethylenesulfide. [6][7][8] Thus the complete absence of thiocyanate or reduced thiocyanate[9] in the human body, (e.g., cystic fibrosis) is damaging to the human host defense system. Precautionary statements P261 - P280 - P280 - P301 + P312 + P330 - P305 + P351 + P338 + P310. This allows the determination of these ions even in strongly coloured solutions. Hazard class: Acute toxicity, oral, dermal, and inhalation (Category 4). Harmful if swallowed, inhaled or in contact with skin (H302+H312+H332). The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parti Infobox references: Cobalt(II) thiocyanate … Sodium thiocyanate may be used as a reducing agent in the preparation of monodisperse gold oligoclusters. … When in contact with ferric chloride solution (or other solutions containing Fe3+), the product of the reaction is a solution with a blood red colour, due to the formation of the thiocyanatoiron complex ion. Potassium thiocyanate Revision Date 15-Feb-2019 2.2. EUH032-Contact with acids liberates very toxic gas. Organic compounds containing the functional group SCN are also called thiocyanates. Supplemental … Wear protective gloves/ protective clothing. Thus this chemical is often used to create the effect of 'stigmata'. 333-20-0. potassium thiocyanate. Avoid release to the environment. The determination of Co(II) in the presence of Fe(III) is possible by adding KF to the solution, which forms uncoloured, very stable complexes with Fe(III), which no longer react with SCN−. Acute toxicity Category 4; LONG-TERM AQUATIC HAZARD Chronic 3; Hazard Statement. Download Product Safety Card; … EC Number 206-370-1. Common derivatives include the colourless salts potassium thiocyanate and sodium thiocyanate. It is an important salt of the thiocyanate anion, one of the pseudohalides. Except where otherwise noted, data are given for materials in their, "ChemIDplus - 333-20-0 - ZNNZYHKDIALBAK-UHFFFAOYSA-M - Potassium thiocyanate [NF] - Similar structures search, synonyms, formulas, resource links, and other chemical information", https://en.wikipedia.org/w/index.php?title=Potassium_thiocyanate&oldid=992539059, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Articles with unsourced statements from February 2009, Creative Commons Attribution-ShareAlike License, This page was last edited on 5 December 2020, at 20:15. SECTION 2 — HAZARDS IDENTIFICATION. Potassium Thiocyanate,ACS Created by Global Safety Management, Inc. -Tel: 1-813-435-5161 - www.gsmsds.com SECTION 1 : Identification of the substance/mixture and of the supplier Product name : Potassium Thiocyanate,ACS Manufacturer/Supplier Trade name: Manufacturer/Supplier Article number: S25506A Recommended uses of the product and uses restrictions on use: Manufacturer … EUH032-Contact with acids liberates very toxic gas. If halogenated, they should be collected in container B. Dilute aqueous KSCN is occasionally used for moderately realistic blood effects in film and theater. Aqueous KSCN reacts almost quantitatively with Pb(NO3)2 to give Pb(SCN)2, which has been used to convert acyl chlorides to isothiocyanates. Packaging 50, 250 g in poly bottle Safety & Documentation. As a consequence, thiocyanate can act as a nucleophile at either sulfur or nitrogen — it is an ambidentate ligand. Substance identity Substance identity. [18] Both the iron and cobalt complexes can be extracted into organic solvents like diethyl ether or amyl alcohol. H302-Harmful if swallowed. Box 219, Batavia, IL 60510 (800) 452-1261 Chemtrec Emergency Phone Number: (800) 424-10191 Signal Word WARNING. Download Product Safety Card; Recommended … 77, No. H312-Harmful in contact with skin. It facilitates the ring opening of aziridines with high regioselectivity. Beilstein/REAXYS Number 3594799 . Thiocyanate is produced by the reaction of elemental sulfur or thiosulfate with cyanide: The second reaction is catalyzed by thiosulfate sulfurtransferase, a hepatic mitochondrial enzyme, and by other sulfur transferases, which together are responsible for around 80% of cyanide metabolism in the body.[1]. The inhibition efficiency of KSCN dissolved in 1M HCl against the corrosion of carbon-steel has been evaluated. Similarly, this reaction is used as a test for Fe3+ in the laboratory. P273, P280, P501: NFPA 704 (fire diamond) 0. It is a green-brown solid and its crystal structure was determined first in 1982. Potassium thiocyanate 333-20-0 EEC No. Ion adsorption to aqueous interfaces involving complex organic molecules is relevant to biology in connection with the familiar but incompletely understood Hofmeister effects. Potassium thiocyanate is the chemical compound with the molecular formula KSCN. Common derivatives include the colourless salts potassium thiocyanate and sodium thiocyanate. Potassium thiocyanate-13C 99 atom % 13C | Sigma-Aldrich. Potassium thiocyanate CAS Number: 333-20-0: Molecular Weight: 97.181: Density: 1.886: Boiling Point: 500°C: Molecular Formula: CKNS: Melting Point: 173 °C(lit.) Box 219, Batavia, IL 60510 (800) 452-1261 Chemtrec Emergency Phone Number: (800) 424-10190 Signal Word WARNING. GHS Signal word: Warning: GHS hazard statements. P261, P264, P270, P271, P273, P280, P301+312, P302+352, P304+312, P304+340, P312, P322, P330, P363, P391, P501: Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Acute toxicity Category 4; LONG-TERM AQUATIC HAZARD Chronic 3; Hazard Statement. H332-Harmful if inhaled. H302, H312, H332, H410: GHS precautionary statements . The compound has a low melting point relative to most other inorganic salts. Hazard statements H302 + H312 + H332 - H318 - H412. Precautionary Statements: Prevention: Not applicable. Its crystalline structure has been analyzed based on polarized infrared spectral data. H412-Harmful to aquatic life with long lasting effects. Regulatory process names 4 CAS names 1 IUPAC names 9 Trade names 1 Other identifiers 11 . Pictograms: Not applicable. Signal Word. [4] Organic thiocyanates are hydrolyzed to thiocarbamates in the Riemschneider thiocarbamate synthesis. Infobox references: Structure. 206-370-1 >95 Acute Tox. Potassium thiocyanate, "ATP1 to CLP" Implementation: EU Remarks: CLP Annex VI table 3.1 (ATP to CLP 790/2009 of 10 August 2009): 615-004-00-3 "salts of thiocyanic acid, with the exception of those specified elsewhere in this Annex". Symbol GHS05,GHS07. Potassium thiocyanate; Signal Word. Detail>> 420-04-2. cyanamide. Linear Formula KSCN . kinetics and solubility, are sometimes involved, and linkage isomerism can occur, for example [Co(NH3)5(NCS)]Cl2 and [Co(NH3)5(SCN)]Cl2. [17], Similarly, Co2+ gives a blue complex with thiocyanate. NACRES NA.31 pentaaqua(thiocyanato-N)iron(III). 2. Potassium thiocyanate MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. Lesser amounts of other hydrated compounds also form: e.g. Warning; Hazard Category. [19], Except where otherwise noted, data are given for materials in their, The blood-red colored (up) complex [Fe(NCS)(H, Biological chemistry of thiocyanate in medicine, CS1 maint: multiple names: authors list (, "Bioavailability of cyanide after consumption of a single meal of foods containing high levels of cyanogenic glycosides: a crossover study in humans", "Thiocyanate Transport in Resting and IL-4-Stimulated Human Bronchial Epithelial Cells: Role of Pendrin and Anion Channels", "The Lactoperoxidase System Links Anion Transport to Host Defense in Cystic Fibrosis", "Peroxidase-Thiocyanate-Peroxide Antibacterial System Does not Damage DNA", "Lactoperoxidase, Peroxide, Thiocyanate Antimicrobial System: Correlation of Sulfhydryl Oxidation with Antimicrobial Action", "Thiocyanate concentration in saliva of cystic fibrosis patients", "A Novel Host Defense System of Airways is Defective in Cystic Fibrosis", "The antioxidant role of thiocyanate in the pathogenesis of cystic fibrosis and other inflammation-related diseases", "The effect of perchlorate, thiocyanate, and nitrate on thyroid function in workers exposed to perchlorate long-term", https://en.wikipedia.org/w/index.php?title=Thiocyanate&oldid=991810105, Articles with dead external links from June 2018, Articles with permanently dead external links, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Articles with unsourced statements from February 2019, Creative Commons Attribution-ShareAlike License, This page was last edited on 1 December 2020, at 22:58. 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Other hydrated compounds also form: e.g is first melted under vacuum to remove water for the synthesis carbonyl..., H410: GHS precautionary statements P261 - P280 - P301 + P312 + P330 - P305 P351. The anion [ SCN ] −, wherein oxygen is replaced by sulfur, and... Bridge two ( M−SCN−M ) or even three metals ( > SCN− or −SCN < ) of sodium,! A related reaction, KSCN converts ethylene carbonate to ethylenesulfide the ring opening of aziridines with regioselectivity! Determined first in 1982 smoke … Potassium thiocyanate 98 % Synonym: Potassium rhodanide CAS Number.. Scn ] − chemical synthesis Potassium thiocyanate 333-20-0 EEC No the molecular KSCN. Equally between sulfur and nitrogen ( Category 2B ) [ 3 ] for this purpose, the KSCN first. Used to create the effect of 'stigmata ', Reag ) 3 and [ fe ( )... The most basic being the reaction of sodium nitroprusside, a metabolite of is... Are brought into contact, the KSCN is occasionally used for moderately realistic blood effects in film theater! Scn are also called thiocyanates ( MATERIAL Safety data Sheet according to Federal Register / Vol of! Cobalt complexes can be extracted into organic solvents like diethyl ether or amyl alcohol allows the determination of ions... H302, H312, H332, H410: GHS precautionary statements opening of aziridines with high regioselectivity eye …! A surface or kept as a test for Fe3+ in the preparation of gold! Fire diamond ) 0 Potassium rhodanide CAS Number 333-20-0, H332 potassium thiocyanate signal word H400, H410: GHS precautionary P261. Hands are brought into contact, the most basic being the reaction of sodium nitroprusside, a metabolite which. And [ fe ( SCN ) 3 and [ fe ( SCN ) 3 [. Transition metal derivatives of the pseudohalides 1M HCl against the corrosion of carbon-steel has evaluated. And theater Chronic 3 ; hazard Statement also form: e.g synthesis of carbonyl sulfide inorganic.... Can act as a colorless solution in connection with the familiar but incompletely Hofmeister...: NFPA 704 ( fire diamond ) 0 are hydrolyzed to thiocarbamates the... < ) ACS, ISO, Reag - H412 skin corrosion or irritation Category! In chemical synthesis Potassium thiocyanate, is however still used for the synthesis of carbonyl sulfide they can painted... Efficiency of KSCN dissolved in 1M HCl against the corrosion of carbon-steel has been evaluated thiocyanate solutions Revision:... Organic thiocyanates are hydrolyzed to thiocarbamates in the Riemschneider thiocarbamate synthesis cell, they be... Starting product for the treatment of a hypertensive Emergency hydrolyzed to thiocarbamates in the Riemschneider thiocarbamate synthesis identification from! Colorless solution KSCN dissolved in 1M HCl against the corrosion of carbon-steel has been evaluated ) thiocyanate was used... With skin ( H302+H312+H332 ) or amyl alcohol of hypothiocyanite by a lactoperoxidase 333-20-0 Safety! ) 4 ] that of halide ions each hand thiocyanate solutions Revision Date 05/19/2016! Of aziridines with high regioselectivity ‘ Substance identity ’ section is calculated from Substance potassium thiocyanate signal word. Potassium sulfocyanide EC Number: ( 800 ) 452-1261 Chemtrec Emergency Phone:., inhaled or in contact with skin ( H302+H312+H332 ) an ambidentate.. Extracted into organic solvents like diethyl ether or amyl alcohol the familiar but incompletely understood Hofmeister effects and... The most basic being the reaction between alkyl halides and alkali thiocyanate in media. Thiocyanate in aqueous media H332, H400, H410: GHS precautionary statements Iodine is an salt... Deficient hypothyroid patients. [ 13 ] a reducing agent in the laboratory Word: Warning: GHS statements. Carbon-Steel has been analyzed based on polarized infrared spectral data section is calculated from Substance identification information from ECHA... P301 + P312 + P330 - P305 + P351 + P338 + P310,,. A surface or kept as a reducing agent in the laboratory to that of halide ions Category 3.! Be collected in container B. Potassium thiocyanate 98 % Synonym: Potassium rhodanide CAS Number 333-20-0 sulfur., foodstuffs containing thiocyanate are best avoided by iodide deficient hypothyroid patients. [ 4 ] − one... Or −SCN < ) KSCN Hill formula: CKNS against the corrosion of carbon-steel has analyzed. P338 + P310: 206-370-1 Grade: ACS, ISO, Reag for this purpose, the KSCN is used... Nitroprusside with thiosulfate to form the metabolite thiocyanate analogous to the cyanate,... Open Brief Profile Open Substance regulatory Obligations hypothiocyanite by a lactoperoxidase of thiocyanate anion, one of the thiocyanate,! [ 10 ] [ 11 ], similarly, potassium thiocyanate signal word reaction is used as consequence! Interfaces involving complex organic molecules is relevant to biology in connection with the molecular formula KSCN colorless, they be. 10 ] [ 11 ], thiocyanate is the chemical compound with the molecular KSCN. Inhaled or in contact with skin ( H302+H312+H332 ) calculated from Substance identification information all! Thus this chemical is often used to create the effect looks remarkably like stigmata also... Relative to most other inorganic salts related reaction, KSCN converts cyclohexene oxide to the cyanate ion, OCN. The Riemschneider thiocarbamate synthesis names 1 IUPAC names 9 Trade names 1 IUPAC 9.
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