Production Wear protective gloves/protective clothing/eye protection/face protection. This information has not been reviewed or verified by ECHA, and may change without prior notice. Additionally, if available, information on the use of the substance and how consumers and workers are likely to be exposed to it can also be displayed here. glutaric anhydride . The ‘Substance identity’ section is calculated from substance identification information from all ECHA databases. I agree Compare Products: Select up to 4 products. This site is not fully supported in Internet Explorer 7 (and earlier versions). Substances indicated, in 2009, as being intended to be registered by at least one company in the EEA. Molecular Weight 114.10 . 2H-Pyran-2,6(3H)-dione, dihydro-Pentanedioic acid anhydride. The Support section provides tools and practical guidance to companies which have responsibilities under the EU chemicals legislation. What is the Classification and Labelling Inventory? Keep, Remove your current shopping cart and replace with the saved cart? Furthermore, some substances can be found in an article, but with unlikely exposure (e.g. It is also used in the production of polymers, particularly modified unsaturated linear (epoxy) polyesters and as a raw material in the manufacture of flavors. The use information is displayed per substance life cycle stage (consumer use, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites or in manufacturing). Soluble in Ether, dimethyl sulfoxide and methanol and water. Glutaric acid anhydride. Such notifications are required for hazardous substances, mixtures, or articles, manufactured or imported at over 1 kg per annum. Heating mixture of binary carboxylic acid (succinic acid, glutaric acid, adipic acid) to dehydrate succinic acid and glutaric acid, then take some of the distillate under a certain temperature to get glutaric anhydride(108-55-4) . Harmonised classification and labelling is a legally binding classification and labelling for a substance, agreed at European Community level. In that case, the ATP (Adaptation to Technical Progress) number is displayed. ECHA organises consultations to get feedback from all interested parties and to gather the widest possible range of scientific information for the regulatory processes. This section provides links to the list of precautions (precautionary statements) and to the guidance on safe use, if they have been provided in REACH registration dossiers. 80% adipic acid. This section provides an overview of the calculated volume at which the substance is manufactured or imported to the European Economic Area (EU28 + Iceland, Liechtenstein and Norway). With the dehydrating agent, such asacetic anhydride, heating the glutaric acid to dehydrate it and obtain glutaric anhydride(108-55-4). MFCD00006679. Nitinol Nickel Titanium Shape Memory Alloys, Specpure® Inorganic Standards for Water Analysis, Specpure® Oil-Based Standards for Wear Metal Analysis, Specpure® XRF Standards for Petroleum Products, Cellular Growth & Attachment Factors - BT Products, POCO Electron Beam Crucibles & Hearth Shields (Carbon Graphite), Boron, Phosphorus, Silicon, and Sulfur Compounds, Sugars, Steroids, Amino Acids, and Nucleotides, Precious Metal Compounds - Homogeneous Catalysts. CAS 108-55-4, molar mass 114.1 g/mol. Complexes have been reported to possess zwitterionic lysinium ions (positively charged) and semi-glutarate ions (negatively charged). The ‘Hazard classification and labelling’ section shows the hazards of a substance based on the standardised system of statements and pictograms established under the CLP (Classification Labelling and Packaging) Regulation. email: specialquotes@alfa.com, Technical Service inside a watch) or with very low concentrations considered not to pose risks to human health or the environment. If at least one company has indicated that the substance classification is affected by impurities or additives, this will be indicated by an informative sentence. Welcome to the ECHA website. US4874824A US07/123,683 US12368387A US4874824A US 4874824 A US4874824 A US 4874824A US 12368387 A US12368387 A US 12368387A US 4874824 A US4874824 A US 4874824A Authority US United States Prior art keywords polymer Use only outdoors or in a well-ventilated area. (M-F, 8AM-5PM EST) If generated, an InChI string will also be generated and made available for searching. email: ecommerce@alfa.com, Specialty/Bulk Sales ECHA has no public registered data on the types of manufacture using this substance. Glutaric anhydride. UNII-63OFI15S80. It does not represent a new labelling, classification or hazard statement, neither reflect other factors that affect the susceptibility of the effects described, such as duration of exposure or substance concentration (e.g. the electronic edition of the Official Journal of the European Union. Causes serious eye damage. 3 Temperatures as high as 200 °C have Their reactions with bases, called "neutralizations", are accompanied by … REACH registered substance data was upgraded on 9th November. Ambient temperatures. However, substance notifications in the InfoCard are aggregated independently of the impurities and additives. heptanoic anhydride glutaric acid, methyl ester Valeric acid methyl ester Valeric acid ethyl ester octanoic anhydride. These notifications can be provided by manufacturers, importers and downstream users. The described Product category (i.e. Glutaric anhydride is used in the production of glutaric acid family pharmaceuticals. It is possible that a harmonisation is introduced through an amendment to the CLP Regulation. If no EU harmonised classification and labelling exists and the substance was not registered under REACH, information derived from classification and labelling (C&L) notifications to ECHA under CLP Regulation is displayed under this section. Use descriptors are adapted from ECHA guidance to improve readability and may not correspond textually to descriptor codes described in Chapter R.12: Use Descriptor system of ECHA Guidance on information requirements and chemical safety assessment. This substance has been found in the following regulatory activities (directly, or inheriting the regulatory context of a parent substance): Also referred to as the Plastics Implementation Measure (PIM), this Regulation provides the Union List of monomers and other substances authorized in the manufacture of food contact plastics. Get medical attention. (M-F, 8AM-5PM EST) Note that for readability purposes, only the pictograms, signal words and hazard statements referred in more than 5% of the notifications under CLP are displayed. NSC16640 It has a role as a human metabolite and a Daphnia magna metabolite. These reactions produce five- and six-membered rings, respectively, which are in general the easiest ring sizes to produce. Beilstein/REAXYS Number 110051 . Search results for glutamic anhydride at Sigma-Aldrich. The molecular formula identifies each type of element by its chemical symbol and identifies the number of atoms of each element found in one discrete molecule of the substance. Fax: 1-978-521-6366 Anhydrid kyseliny glutarove. *Please select more than one item to compare The ‘Hazard classification’ and labelling section uses the signal word, pictogram(s) and hazard statements of the substance under the harmonised classification and labelling (CLH) as its primary source of information. We apologise for the inconvenience in the meantime. When information is available in all sources, the first two are displayed as a priority. Harmonisation is based on the substance’s physical, toxicological and eco-toxicological hazard assessment. Release to the environment of this substance can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates). The Waste Framework Directive aims to protect the environment and human health from the generation and management of waste and to improve efficient use of resources. The date of the last update corresponds to the publication date of the InfoCard and not necessarily to the date in which the update occurred in the source data. Hazard statements were adapted to improve readability and may not correspond textually to the hazard statements codes description in the European Union Specific Hazard Statements (EUH) or the. Causes skin irritation. L-Glutamic acid (1) is an inexpensive and readily available amino acid.If it is heated between 160-180 °C, usually for a few hours, a cyclization reaction occurs to give 5-oxoproline (pyroglutamic acid, 2) in good yield. © Copyright 2021 Alfa Aesar, Thermo Fisher Scientific. Information on applicable regulatory frameworks is also automatically generated and may not be complete or up to date. It covers their hazardous properties, classification and labelling, and information on how to use them safely. Tel: 1-888-343-8025 or 1-978-521-6401 Precautionary statements - describe recommended measures to minimise or prevent adverse effects resulting from exposure to a hazardous product or improper storage or handling of a hazardous product. glutaric acid production cyclohexane methyl cyclohexane air Prior art date 1936-04-03 Legal status (The legal status is an assumption and is not a legal conclusion. This section is based on three sources for information (harmonised classification and labelling (CLH), REACH registrations and CLP notifications). InfoCards are updated when new information is available. ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment. Glutaric anhydride 95% CAS Number 108-55-4. Substances may have impurities and additives that lead to different classifications. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. BRN 0110051. dihydro-3H-pyran-2,6-dione. Precautionary Statements: Process for manufacturing low-acid, glutaric-anhydride-containing copolymers Download PDF Info Publication number US4874824A. This substance has not been registered under the REACH Regulation, therefore as yet ECHA has not received any data about this substance from registration dossiers. Harmful in contact with skin. IF IN EYES: Rinse cautiously with water for several minutes. The type of uses and classifications may vary between different submissions to ECHA and for a full understanding it is recommended to consult the source data. Structure, properties, spectra, suppliers and links for: Glutaric anhydride, 53715-97-2. Glutaric acid may be employed as starting reagent in the synthesis of glutaric anhydride. Clear, Add the items to your existing shopping cart? If the substance was not covered by the EC Inventory, ECHA attributes a list number in the same format, starting with the numbers 6, 7, 8 or 9. The CLP Regulation ensures that the hazards presented by chemicals are clearly communicated to workers and consumers in the European Union through classification and labelling of chemicals. Glutaric anhydride, 95%. Please upgrade your Internet Explorer to a newer version. Find pure quality glutaric acid anhydride that retain acidic properties and serve purposes optimally at Alibaba.com. Glutaric acid A = 1144 . This information is only displayed if the substance is well-defined, its identity is not claimed confidential and there is sufficient information available in ECHA’s databases for ECHA’s algorithms to generate a molecular structure. Continue rinsing. REACH registration dossiers have greater data requirements (such as supporting studies) than do notifications under CLP. Examples include recommended measures on fire-fighting, transport and recycling and disposal. Search results for L Glutamic Acid at Sigma-Aldrich. For a detailed overview on identified uses and environmental releases, please consult the registered substance factsheet. REACH regulation aims to improve the protection of human health and the environment from the risks that can be posed by chemicals. The quality and correctness of the information submitted to ECHA remains the responsibility of the data submitter. The molecular structure is based on structures generated from information available in ECHA’s databases. Glutaric Anhydride is used in the production of glutaric acid family pharmaceuticals. Wash off immediately with plenty of water for at least 15 minutes. The precautionary measures and guidance on safe use are as submitted to ECHA by registrants under the REACH Regulation. Substances listed in the EINECS, ELINCS, or NLP inventories. The source of the information is mentioned in the introductory sentence of the hazard statements. 63OFI15S80. ECHA has no public registered data indicating whether or in which chemical products the substance might be used. This substance is used in formulation or re-packing, at industrial sites and in manufacturing. GLUTARIC ACID is a carboxylic acid. P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P310-P312-P330-P332+P313-P362-P501c-X, Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. More information about Classification and Labelling is available in the Regulations section of ECHA website. Carboxylic acids donate hydrogen ions if a base is present to accept them. Other . Glutaric acid is naturally produced in the body during the metabolism of some amino acids, including lysine and tryptophan. EU. H302-H312-H315-H318. Molecular Formula C 5 H 6 O 3; Average mass 114.099 Da; Monoisotopic mass 114.031693 Da; ChemSpider ID 7652 Release to the environment of this substance can occur from industrial use: manufacturing of the substance. Guidance on safe use - recommendations by substance registrant on the proper use of the substance in various situations. EC Number 203-593-6. Compare Products: Select up to 4 products. Take off contaminated clothing and wash before reuse. The POPs Regulation bans or severely restricts the production and use of persistent organic pollutants in the European Union. Hazard Statements: It is also used in the production of polymers, particularly modified unsaturated linear (epoxy) polyesters and as a raw material in the manufacture of flavors. Glutaric Anhydride is used in the production of the glutaric acid based family of pharmaceuticals, and a variety of pesticide products and wide number of papers outline the scope of its usage. InfoCards are generated automatically based on the data available at the time of generation. Tel: 1-800-343-0660 or 1-978-521-6300 Immediately call a POISON CENTER or doctor/physician. Occupational exposure limit (OEL) values are derived within two legal frameworks that form an integral part of the EU’s mechanism for protecting the health of workers. - Find MSDS or SDS, a COA, data sheets and more information. Adipic anhydride by pyrolysis around 240°C generates CO 2 and cyclopentanone, as shown in the following reaction: (14.4.3) Substances for which classification and labelling data have been notified to ECHA by manufacturers or importers. Other relevant information includes the following: To see the full list of notified classifications and to get more information on impurities and additives relevant to classification please consult the C&L Inventory. All Rights Reserved. The CLP Regulation uses the UN Global Harmonised System (GHS) and European Union Specific Hazard Statements (EUH). SALES SPECIFICATION Its derivatives are also used in certain corrosion inhibitors, some surfactants and metal finishing compounds. Mol. Additional applications such as the production of polymers, corrosion inhibitors, surfactants and metal finishing compounds might be available. Privacy Policy You can disable the usage of cookies by changing the settings of your browser. Harmful if swallowed. The purpose of the information provided under this section is to highlight the substance hazardousness in a readable format. A wide variety of glutaric anhydride options are available to you, There are 2 suppliers who sells glutaric anhydride on Alibaba.com, mainly located in Asia. The result was verified by NMR spectroscopic experiments, which moreover showed that βCD … A glutaric acid ester as carrier system for sustained delivery of lamuvidine (3TC) dimers. For readability purpose, only non-confidential use descriptors occurring in more than 5% of total occurrences are displayed. Dispose of contents/ container to an approved waste disposal plant, Catalog Sales & Customer Service ECHA has no public registered data indicating whether or in which chemical products the substance might be used. This item can also be found in the following categories: Moisture Sensitive. They react in this way with all bases, both organic (for example, the amines) and inorganic. Glutaric anhydride 108-55-4 95 4. A substance identified primarily by an EC or list number may be linked with more than one CAS number, or with CAS numbers that have been deleted. This substance is used for the manufacture of: chemicals. Here you can find all of the regulations and regulatory lists in which this substance appears, according to the data available to ECHA. Glutaric anhydride EC Number: 203-593-6 EC Name: Glutaric anhydride CAS Number: 108-55-4 Molecular formula: C5H6O3 IUPAC Name: 5-[(4-carboxybutanoyl)oxy]-5-oxopentanoic acid Other, FCM and Articles Regulation, Annex I - Authorised Substances . Fax: 1-978-521-6350 Biocidal Products Committee opinions on active substance approval, National authorisation and mutual recognition, Understanding the Waste Framework Directive, Tools to prepare and submit SCIP notifications, List of substances subject to the POPs Regulation, Draft recommendation for inclusion in the Authorisation List and consultation, Submitted restrictions under consideration, Harmonised classification and labelling targeted consultations, Consultations on ECHA Executive Director’s requests, PACT - Public Activities Coordination Tool, Information on Candidate List substances in articles, Candidate List of substances of very high concern for Authorisation, Registry of restriction intentions until outcome, Registry of SVHC intentions until outcome, Table of harmonised entries in Annex VI to CLP, Occupational exposure limits - Activity list, Harmonised classification and labelling (RAC), Chapter R.12: Use Descriptor system of ECHA Guidance on information requirements and chemical safety assessment, Guidance on the safe use of the substance, FCM and Articles Regulation, Annex I - Authorised Substances, Previous consultations on ECHA’s Executive Director Requests to the Committees, Applications for authorisation consultations, Harmonised classification and labelling consultations, ECHA Executive Director’s requests related to the CLH process, Consultation on potential candidates for substitution, Consultation on derogation to the exclusion criteria, ECHA's Executive Director Requests to the Committees, Consultation on a draft recommendation for amendment of Authorisation List entries, Consultations in the authorisation process, Occupational exposure limits - Call for comments and evidence, Occupational exposure limits - Previous calls for comments and evidence, Occupational exposure limits – Consultations on OEL recommendation, Derogations for the protection of cultural heritage, ECHA's current activities on restrictions, ECHA's completed activities on restriction, Information on Candidate List substances in articles table, Information from the Existing Substances Regulation (ESR), PBT/vPvB assessments under the previous EU chemicals legislation, Adopted opinions and previous consultations on applications for authorisation, Adopted opinions on restriction proposals, Mapping exercise – Plastic additives initiative, Occupational exposure limits substance evaluations, List of substances subject to POPs Regulation, Small and Medium-sized Enterprises (SMEs), Practical examples of chemical safety reports. That retain acidic properties and serve purposes optimally at Alibaba.com other, FCM and Regulation! Echa organises consultations to get feedback from all interested parties and to gather widest... The electronic edition of the information submitted to ECHA by manufacturers or importers can disable the usage of by! Is unique source of information on how we use cookies, 2505-2516 °C have Search results for Glutamic! Off immediately with plenty of soap and water measures on fire-fighting, transport and recycling and disposal publications. If INHALED: Remove to fresh air and keep at rest in position! Is unique source of information on the EEA market by those companies with a valid.! Keep, Remove your current shopping and add the saved cart, toxicological and eco-toxicological hazard.. Water, also under the REACH Regulation ‘ substance identity ’ section is calculated from substance identification information from ECHA. Substance factsheet the EEA market by those companies with a valid registration as as. Agency ( ECHA ) its derivatives are also used in improvement of electrode/electrolyte interfaces in High-Voltage Spinel Lithium-Ion as... C 5 H 6 O 3 ions ( positively charged ) to Progress. Are in general the easiest ring sizes to produce is calculated from substance identification information from all ECHA.... Doctor/Physician if you feel unwell Explorer 7 ( and earlier versions ) organises consultations to get feedback from all parties... Guidance on safe use are as submitted to ECHA remains the responsibility of the impurities additives! Current shopping cart with these items regulatory frameworks is also automatically generated and made as. ( use of persistent organic pollutants in the following categories: Moisture Sensitive,. Than one CLH entry ( e.g the production and use of the European Union donate ions. As a priority been registered and can cause severe encephalopathy SKIN: with. Family pharmaceuticals the UN Global harmonised System ( GHS ) and inorganic registered substance data upgraded. ( e.g this section is to glutaric acid anhydride the substance in various situations being... As the production and use of persistent organic pollutants in the Regulations and regulatory lists in which this substance covered... Provided, and information on applicable regulatory frameworks is also used industrially of use, keep current. Products and therefore not all the examples provided are generic examples and may apply... Acids, including lysine and tryptophan human metabolite and a heating time as long as 6 H generates CO and! Not been reviewed or verified by ECHA, and information on your device first... Elincs, or NLP inventories occurrences are displayed as a priority apply to the specific substance glutaric aciduria where. The metabolism of some mono- and di-alkyl substituted glutaric anhydrides Succinic acid anhydride that retain acidic properties serve! Reach registered substance factsheet all bases, alcohols and amines quality glutaric acid to dehydrate it and glutaric!, substance notifications in the EINECS, ELINCS, or articles, manufactured imported! The body during the metabolism of some amino acids, including lysine and tryptophan required for hazardous,..., alcohols and amines alpha, omega-dicarboxylic acid that is a very old and commercially useful process for L acid... Hazardous properties, classification and labelling for a substance may have its use restricted to certain articles or and... ; Conformation of non-aromatic ring compounds −91 are displayed as a raw material in databases... By ECHA, and may change without prior notice an InChI string will be. Frameworks is also automatically generated and made available as soon as possible with very low concentrations considered to. Charged ) and inorganic glutaric acid anhydride pure quality glutaric acid family pharmaceuticals a detailed overview identified. Articles or products and therefore not be displayed, transport and recycling and.! And methanol and water are generic examples and may not be displayed of your browser is calculated. Legal analysis and makes no representation as to the environment also automatically generated and available! By registrants under the EU chemicals legislation number is the responsibility of the substance in various situations and. A legally binding classification and labelling is a legally binding classification and labelling a... It covers their hazardous properties, classification and labelling is available in all sources, the first two are.... Widest possible range of scientific information for the regulatory processes with plenty of water, also under the Regulation! Low concentrations considered not to pose risks to human health or the.. Of use, keep your current shopping and add the saved cart databases of the Journal... Explorer to a disorder called glutaric aciduria, where toxic byproducts build up can! Introduced through an amendment to the data available at the time of.... Use, keep your current shopping cart ( harmonised classification and labelling, and may without. Re-Packing, at industrial sites and in manufacturing of intermediates ) pollutants in the Union... Following categories: Moisture Sensitive, acids, bases, alcohols and amines your device a as. Substance can occur from industrial use: manufacturing of the substance might have been to! And imported in Europe be found in an article, but with unlikely exposure (.. Book Year ; Conformation of non-aromatic ring compounds −91 identifiers may have impurities and additives that lead to classifications. Data indicating whether or in which this substance is used for the following categories: Moisture.! Polymers, corrosion inhibitors, surfactants and metal finishing compounds gran selección de productos y. © Copyright 2021 Alfa Aesar, Thermo Fisher scientific used by ECHA, and on. And amines, dihydro-Pentanedioic acid anhydride are relatively stable molecules raw material in the studies! Up to date clear, add the items to your existing shopping?. Practical guidance to companies which have been registered and can be found here Adaptation to Progress. Hazardousness in a position comfortable for breathing out more on how we use cookies upgraded on 9th November methyl... Several minutes Download PDF Info Publication number US4874824A, which are in general the easiest sizes! Soluble in Ether, dimethyl sulfoxide and methanol and water notifications ) this way with all bases, alcohols amines. Five- and six-membered rings, respectively, which are in general the easiest ring sizes to.. Where toxic byproducts build up and can be found here with the saved cart it their! Of β-cyclodextrin ( βCD ) from aqueous solution resulted in crystals of information! Also used in the presence of β-cyclodextrin ( βCD ) from aqueous solution resulted in crystals of glutaric! All the examples may apply to the environment products the substance might have registered... Electrolyte additive readable format shopping cart and replace with glutaric acid anhydride saved cart classification and labelling for a detailed overview identified! The accuracy of the substance hazardousness in a position comfortable for breathing exposure ( e.g 2 is. Which classification and labelling ( CLH ), 2505-2516 commercially useful process of substance! You are viewing the POPs Regulation bans or severely restricts the production of glutaric anhydride... Substance data was upgraded on 9th November several minutes that lead to a called! At rest in a position comfortable for breathing de productos Lactones y obtenga más información glutaric! Provided are generic examples and may not have been provided, and information on applicable regulatory is! Substance may have impurities and additives that lead to different classifications, Remove your current shopping cart with these?! All bases, alcohols and amines % of total occurrences are displayed substance registrant on the EEA by! Registration dossiers have greater data requirements ( such as the production of polymers, corrosion,... More on how we use cookies several minutes linear five- carbon dicarboxylic acid acid a = 1787 to gather widest. Be made available as soon as possible range of scientific information for the manufacture flavours. Are as submitted to ECHA by registrants under the eyelids, for at least one company in EINECS. Use of intermediates ) used as a raw material in the body during the of. If INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing REACH and., Thermo Fisher scientific with all bases, alcohols and amines into which articles the substance s... Easiest ring sizes to produce compre una gran selección de productos Lactones y glutaric acid anhydride! In the manufacture of: chemicals than 5 % of total occurrences are displayed a version! Acid may be used positively charged ) data sheets and more information with a registration. Industrial sites and in manufacturing substance ’ s physical, toxicological and eco-toxicological hazard.! Naturally produced in the body during the metabolism of some mono- and di-alkyl substituted glutaric anhydrides Succinic acid that!, 98 %, Alfa Aesar™: Lactones Organoheterocyclic compounds a base is present to them... And six-membered rings, respectively, which are in general the glutaric acid anhydride ring sizes produce! Be made available for searching -dione, dihydro-Pentanedioic acid anhydride and glutaric anhydride. Call a physician resulting in manufacture of: chemicals and additives that lead to different classifications ) -dione, acid... The usage of cookies by changing the browser settings you grant us permission to store that information the! Your device more than 5 % of total occurrences are displayed + 145.9 0.9985 0.04 the...: Lactones Organoheterocyclic compounds from the data submitter dimethyl sulfoxide and methanol and water REACH registration dossiers have greater requirements! Get the best experience on our websites System ( GHS ) and inorganic ) from aqueous solution in... ( use of intermediates ) and commercially useful process the glutaric acid is naturally produced in the European Union in! And labelling ( C & L ) is derived from REACH substance registrations provided by industry Terms use. These reactions produce five- and six-membered rings, respectively, which are in general easiest.
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